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Table 4 Common GO categories enriched in the different expression datasets.

From: Meta-analysis of expression signatures of muscle atrophy: gene interaction networks in early and late stages

 

K

L

J

R

W

St

Sc

Tot

Array platform type

Membrane

cDNA

cDNA

cDNA

Affy

Affy

cDNA

 

Muscle fibre composition

Fast

mixed

mixed

fast

mixed

slow

mixed

 

Organism

RN

RN

MM

MM

HS

RN

RN

 

Biological Process

        

Response to radiation

X

X

 

X

X

 

X

5

Response to hypoxia

 

X

X

X

X

 

X

5

Glucose homeostasis

 

X

X

X

X

 

X

5

Cellular metabolism

X

X

X

X

   

4

Ion homeostasis

 

X

X

  

X

X

4

Macromolecule metabolism

X

X

X

X

   

4

Muscle development

X

X

X

X

   

4

Negative regulation of enzyme activity

X

X

X

X

   

4

Regulation of cell growth

X

X

X

X

   

4

Transport

  

X

X

 

X

X

4

Biomineral formation

X

X

X

X

   

4

Biosynthesis

X

X

X

X

   

4

Muscle contraction

X

X

X

X

   

4

Osteoblast differentiation

X

X

X

X

   

4

Regulation of coagulation

  

X

X

 

X

X

4

Response to chemical stimulus

X

X

X

X

   

4

Autophagy

 

X

X

X

   

3

Striated muscle contraction

    

X

X

X

3

Adult behaviour

 

X

X

   

X

3

Catabolism

 

X

X

X

   

3

Molecular Function

        

Coenzyme binding

 

X

X

X

X

X

X

6

Transferase activity, transferring alkyl or aryl (other than methyl) groups

X

X

X

X

 

X

X

6

Oxidoreductase activity

 

X

X

X

X

X

X

6

Cytoskeletal protein binding

X

X

 

X

X

X

X

6

Growth factor binding

X

X

X

  

X

X

5

Primary active transporter activity

X

X

X

X

  

X

5

Carbon-oxygen lyase activity

 

X

 

X

X

X

X

5

Ligand-dependent nuclear receptor activity

 

X

X

 

X

X

X

5

Phospholipid binding

 

X

X

X

X

 

X

5

Translation factor activity, nucleic acid binding

X

X

X

X

  

X

5

Cation transporter activity

 

X

X

X

  

X

4

Peptidase activity

X

X

   

X

X

4

Hydrolase activity, acting on glycosyl bonds

X

X

  

X

 

X

4

Metal ion transporter activity

 

X

X

X

 

X

 

4

Electron carrier activity

  

X

X

 

X

X

4

Intramolecular transferase activity

 

X

 

X

 

X

X

4

Iron-sulfur cluster binding

  

X

X

X

 

X

4

L-ascorbic acid binding

 

X

X

X

  

X

4

Ligase activity, forming carbon-oxygen bonds

 

X

X

 

X

 

X

4

Diacylglycerol binding

X

X

X

X

   

4

Fatty acid binding

  

X

X

 

X

X

4

GTP-dependent protein binding

  

X

X

X

X

 

4

Transcription factor binding

 

X

X

X

  

X

4

Transferase activity, transferring phosphorus-containing groups

 

X

X

  

X

X

4

Cellular Component

        

Cytoplasm

X

X

X

X

   

4

Glycerol-3-phosphate dehydrogenase complex

 

X

X

X

  

X

4

Intracellular non-membrane-bound organelle

X

X

X

X

   

4

Mitochondrial envelope

X

X

X

X

   

4

Organelle inner membrane

X

X

X

X

   

4

Ribonucleoprotein complex

X

X

X

X

   

4

Ribosome

X

X

X

X

   

4

Insulin-like growth factor binding protein complex

 

X

X

X

   

3

Intracellular membrane-bound organelle

 

X

X

X

   

3

Intracellular organelle

 

X

X

X

   

3

Organelle membrane

 

X

X

X

   

3

Soluble fraction

 

X

X

X

   

3

Intracellular

    

X

X

X

3

Organelle envelope

 

X

X

X

   

3

Proteasome complex (sensu Eukaryota)

 

X

X

X

   

3

Basement membrane

X

 

X

X

   

3

Cytoskeleton

X

X

 

X

   

3

  1. Symbols are as in the Table 3. X indicates if the category is significantly enriched in the corresponding study (FDR < = 0.1).