Table 1 Signature gene sets for OTSCC
From: Transcriptomic dissection of tongue squamous cell carcinoma
| Â | Symbol | Probe ID | Gene Name | Location |
|---|---|---|---|---|
Upregulated genes in OTSCC | ||||
| Â | MMP1 | 204475_at | matrix metalloproteinase 1 | 11q22.3 |
| Â | MMP10 | 205680_at | matrix metalloproteinase 10 | 11q22.3 |
| Â | MMP3 | 205828_at | matrix metalloproteinase 3 | 11q22.3 |
| Â | MMP12 | 204580_at | matrix metallopeptidase 12 | 11q22.3 |
| Â | PTHLH | 211756_at | parathyroid hormone-like hormone | 12p12.1-p11.2 |
| Â | INHBA | 210511_s_at | inhibin, beta A | 7p15-p13 |
| Â | LAMC2 | 202267_at | laminin, gamma 2 | 1q25-q31 |
| Â | IL8 | 202859_x_at | interleukin 8 | 4q13-q21 |
| Â | KRT17 | 205157_s_at | keratin 17 | 17q12-q21 |
| Â | COL1A2 | 202404_s_at | collagen, type I, alpha 2 | 7q22.1 |
| Â | IFI6 | 204415_at | interferon, alpha-inducible protein 6 | 1p35 |
| Â | ISG15 | 205483_s_at | ISG15 ubiquitin-like modifier | 1p36.33 |
| Â | PLAU | 205479_s_at | plasminogen activator, urokinase | 10q24 |
| Â | GREM1 | 218468_s_at | gremlin 1 | 15q13-q15 |
| Â | MMP9 | 203936_s_at | matrix metallopeptidase 9 | 20q11.2-q13.1 |
| Â | IFI44 | 214453_s_at | interferon-induced protein 44 | 1p31.1 |
| Â | CXCL1 | 204470_at | chemokine (C-X-C motif) ligand 1 | 4q21 |
Downregulated genes in OTSCC | ||||
| Â | KRT4 | 213240_s_at | keratin 4 | 12q12-q13 |
| Â | MAL | 204777_s_at | mal, T-cell differentiation protein | 2cen-q13 |
| Â | CRNN | 220090_at | Cornulin | 1q21 |
| Â | SCEL | 206884_s_at | Sciellin | 13q22 |
| Â | CRISP3 | 207802_at | cysteine-rich secretory protein 3 | 6p12.3 |
| Â | SPINK5 | 205185_at | serine protease inhibitor, Kazal type 5 | 5q32 |
| Â | CLCA4 | 220026_at | chloride channel, calcium activated, family member 4 | 1p31-p22 |
| Â | ADH1B | 209612_s_at 209613_s_at | alcohol dehydrogenase IB (class I), beta polypeptide | 4q21-q23 |
| Â | P11 | 206605_at | 26 serine protease | 12q13.1 |
| Â | TGM3 | 206004_at | transglutaminase 3 | 20q11.2 |
| Â | RHCG | 219554_at | Rhesus blood group, C glycoprotein | 15q25 |
| Â | PPP1R3C | 204284_at | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 10q23-q24 |
| Â | CEACAM7 | 206199_at | carcinoembryonic antigen-related cell adhesion molecule 7 | 19q13.2 |
| Â | HPGD | 203914_x_at | hydroxyprostaglandin dehydrogenase 15-(NAD) | 4q34-q35 |
| Â | CFD | 205382_s_at | D component of complement (adipsin) | 19p13.3 |
| Â | ABCA8 | 204719_at | ATP-binding cassette, sub-family A (ABC1), member 8 | 17q24 |
| Â | CLU | 222043_at | Clusterin | 8p21-p12 |
| Â | CYP3A5 | 214235_at | cytochrome P450, family 3, subfamily A, polypeptide 5 | 7q21.1 |