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Table 2 Selected biological processes that altered in OTSCCs *

From: Transcriptomic dissection of tongue squamous cell carcinoma

GO Name

GO ID

% Change **

p-value

Enhanced

   

Collagen catabolism

GO:0030574

38.9

2.7 E-09

Positive regulation of chemotaxis

GO:0050921

33.3

0.0029

Phosphate transport

GO:0006817

21.7

1.5 E-12

Extracellular matrix organization and biogenesis

GO:0030198

12.9

0.00089

Positive regulation of I-kappaB kinase/NF-kappaB cascade

GO:0043123

8.8

0.00038

Suppressed

   

Superoxide release

GO:0042554

40.0

0.0015

Keratinization

GO:0031424

33.3

1.1 E-05

Hydrogen peroxide metabolism

GO:0042743

25.0

0.0042

Response to hydrogen peroxide

GO:0042542

22.2

0.0053

Keratinocyte differentiation

GO:0030216

21.1

8.0 E-05

  1. * The complete lists of enhanced and suppressed biological processes (BP), molecular functions (MF) and cellular components (CC) in OTSCCs were presented in Supplement Table S3 and S4, respectively.
  2. ** The percent of genes exhibiting expressional changes among all genes that constitutes a specific GO entity.
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BMC Genomics

ISSN: 1471-2164

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