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Figure 2 | BMC Genomics

Figure 2

From: The transcriptome of a complete episode of acute otitis media

Figure 2

Transcript signature of AOM with NTHi. A. Principal component analysis of sample variation. Colors of symbols indicate different times and shapes of symbols indicate different treatments. B. 4-way Venn diagram with number of genes differentially expressed with NTHi versus saline treatment as analyzed by four statistical methods. C. Heat map for 3657 significant genes identified by the combined statistical analysis, comparing time course of saline treatment to NTHi treatment. The final set of altered genes was defined by combining genes that were significant by 2 statistical methods: variance modeling (raw or normalized data), curve fitting, or 2-way ANOVA). D. Expression profiles of four clusters of up-regulated transcripts, showing induction at different times after NTHi inoculation.

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