Phenotype
|
BPT p-value
|
|---|
BD | 2.4e-02§
|
BMI | 1.0e-12* |
CD | 1.9e-06* |
CPD | 6.3e-01 |
HDL | 2.2e-20* |
Height | 3.9e-90* |
LDL | 2.6e-17* |
MS | 3.3e-03§
|
PrCa | 1.1e-01 |
SBP | 9.8e-08* |
SCZ | 4.1e-07* |
T2D | 9.8e-03§
|
TG | 1.5e-16* |
UC | 3.2e-06* |
WHR | 5.8e-06* |
- Significance of miRNA enrichment in 15 phenotypes. Reported are the binomial proportion test (BPT) p-values for miRNA target regions compared with intergenic SNPs for all phenotypes. CPD and PrCa do not reach nominal statistical significance; BD, MS, and T2D would not pass strict multiple testing criteria for 15 phenotypes – BD, Bipolar Disorder; BMI, Body Mass Index; CD, Crohn's disease; CPD, Cigarettes per Day; HDL, High density lipoprotein; LDL, Low density lipoprotein; MS, multiple sclerosis; PrCa, prostate cancer; SBP, systolic blood pressure; SCZ, Schizophrenia; T2D, Type 2 Diabetes; TG, triglycerides; UC, Ulcerative Colitis; WHR, Waist to Hip Ratio. § Nominally significant (not significant after controlling for multiple testing); * Significant.
