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Figure 5 | BMC Genomics

Figure 5

From: The pathogenic human Torsin A in Drosophila activates the unfolded protein response and increases susceptibility to oxidative stress

Figure 5

Transcripts of some ER stress sensors, chaperones, components of ERAD, and ATG8b were significantly altered in the HTorAΔE-expressing brains. The amount of ATF4, ATF6, calreticulin (A), ERp60, PDI, dGRP170, P58IPK (B), Hrd1, Hrd3, Derlin-1, EDEM1, EDEM2 (C) and ATG8b (D) transcripts in the HTorAΔE-expressing brains was significantly different from those of the HTorAWT-expressing brains.

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