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Table 1 Top 20 regulated protein coding genes in the RFP fraction

From: Ribosome profiling reveals translation control as a key mechanism generating differential gene expression in Trypanosoma cruzi

Upregulated

Annotation

Feature ID

log2FC(MT/E)

FDR

hypothetical protein

TcCLB.510323.60

11.93

5.55E-37

trans-sialidase putative

TcCLB.435601.10

11.10

3.43E-27

hypothetical protein conserved

TcCLB.506859.230

10.79

1.04E-32

hypothetical protein

TcCLB.509007.50

10.47

2.09E-32

receptor-type adenylate cyclase putative

TcCLB.428999.20

10.43

4.90E-09

trans-sialidase Group II putative

TcCLB.511585.230

10.42

1.04E-32

mucin-associated surface protein MASP putative

TcCLB.507957.320

10.38

1.05E-13

hypothetical protein

TcCLB.509433.10

10.02

3.30E-29

cyclin putative

TcCLB.509455.140

10.01

1.05E-25

DNA polymerase delta subunit 2 putative

TcCLB.509455.70

9.88

1.46E-29

hypothetical protein

TcCLB.507859.46

9.62

2.14E-08

hypothetical protein conserved

TcCLB.511545.170

9.61

1.75E-28

mucin-associated surface protein MASP putative

TcCLB.506599.100

9.58

2.06E-25

engulfment and cell motility domain 2 putative

TcCLB.509599.164

9.55

4.42E-11

hypothetical protein conserved

TcCLB.509769.20

9.26

9.15E-27

trans-sialidase putative

TcCLB.505363.19

9.13

9.80E-20

ATP-dependent DEAD/H RNA helicase putative

TcCLB.506777.10

9.07

2.26E-06

amino acid permease putative

TcCLB.509167.40

8.94

1.03E-25

protein kinase putative casein kinase I putative

TcCLB.510247.20

8.88

2.78E-23

phosphatidylinositol 3-kinase catalytic subunit putative

TcCLB.511709.19

8.86

1.63E-25

Downregulated

Annotation

Feature ID

log2FC(MT/E)

FDR

40S ribosomal protein S33 putative

TcCLB.506413.30

NA

4.72E-09

hypothetical protein conserved

TcCLB.506659.35

NA

8.80E-06

hypothetical protein conserved

TcCLB.508207.54

NA

4.59E-03

hypothetical protein conserved

TcCLB.509599.120

NA

7.19E-04

hypothetical protein conserved

TcCLB.511527.82

NA

2.25E-02

anti-silencing protein ASF 1 putative

TcCLB.511417.100

NA

2.15E-03

hypothetical protein conserved

TcCLB.510515.120

NA

1.34E-02

hypothetical protein conserved

TcCLB.507611.50

NA

5.81E-03

hypothetical protein conserved

TcCLB.511529.50

NA

1.44E-03

RNA polymerase I

TcCLB.504041.4

NA

5.55E-03

hypothetical protein

TcCLB.504449.40

NA

1.16E-02

hypothetical protein

TcCLB.508277.310

NA

3.51E-02

hypothetical protein conserved

TcCLB.507631.10

NA

4.28E-02

60S ribosomal protein L37a putative

TcCLB.511145.46

−7.37

1.26E-04

kinetoplast-associated protein 3 KAP3

TcCLB.511529.80

−7.36

1.20E-12

nucleoside phosphorylase putative

TcCLB.506865.2

−7.10

2.16E-12

hypothetical protein conserved

TcCLB.511189.84

−6.86

2.50E-05

MP44 putative

TcCLB.506925.390

−6.85

1.55E-04

hypothetical protein conserved

TcCLB.511751.166

−6.83

1.10E-03

hypothetical protein conserved

TcCLB.510289.99

−6.81

1.85E-04

  1. NA: genes with zero counts in the MT stage.