Fig. 8

Urease gene cluster. a The size and organization of C. sordellii urease genes is illustrated. Overall homology of individual proteins to (1) H. pylori and (2) C. perfringens is depicted by colored bars for (+) % similarity and (=) % identity located below each gene. The scale is defined with red > 90 % and cyan < 20 %. b The urease enzyme structure from H. pylori (PDBID: 1E9Z) [66] and the urea channel structure from H. pylori (PDBID: 3UX4) [67] are both shown to illustrate the degree of conservation with corresponding C. sordellii urease proteins near the functional sites. Using the same scale for a, residues colored in red are conserved across H. pylori, C. perfringens and C. sordellii, while residues colored in cyan are not conserved