Fig. 2

Classification of TFTRs according to relative orientation. 663 TFTRs from M. tuberculosis (MTB, 52 TFTRs), M. avium subspecies paratuberculosis (MAP, 110 TFTRs), M. marinum (MM, 124 TFTRs), M. ulcerans (MUL, 88 TFTRs), M. gilvum (MGIL, 129 TFTRs) and M. smegmatis (MSM, 160 TFTRs) were divided into three groups according to their genome context. a 408 TFTRs (33 in MTB, 64 in MAP, 77 in MM, 51 in MUL, 87 in MGIL and 110 in MSM) are encoded divergently to their neighbours. Here, the TFTR-encoding gene is located on the left side, but the positions of this gene and its divergent neighbour are interchangeable. b 146 TFTRs (13 in MTB, 31 in MAP, 26 in MM, 18 in MUL, 26 in MGIL and 32 in MSM) are likely co-transcribed with their upstream or downstream genes as the intergenic DNAs separating them are less than 35 bp. c 109 TFTRs (6 in MTB, 15 in MAP, 21 in MM, 19 in MUL, 16 in MGIL and 18 in MSM) show neither of the two aforementioned orientations