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Fig. 2 | BMC Genomics

Fig. 2

From: Subtelomere organization in the genome of the microsporidian Encephalitozoon cuniculi: patterns of repeated sequences and physicochemical signatures

Fig. 2

Distribution of EXT sub-blocks illustrating extensive variations of chromosome ends organisation. a. The assignation to two main types of EXT organization was performed on the basis of an anchoring with either recombination site R01 (on the right) or R02 (on the left) to the conserved SUB region. Breaks within EXT blocks are indicated by vertical red bars. Fusion events are marked by circles. The discontinuous lines connect the two recombination sites involved in the fusion. The inverted copy of EXT6-2 is shown by an arrow.The inverted triangle indicates that EXT9 contains divergent SUB-2 and EXT1-1 sequence presenting large deletions. Colour gradation was used to represent the different EXT sub-sequences issuing from a same EXT repeat. The scale has been conserved to represent the different EXT sub-sequences. b. Distribution of the recombination sites (R) delimiting EXT sub-blocks. These sites are often hot spots of sequence rearrangement and were identified by their telomere-associated distal sequence which was conserved after genetic events. The two IIIβ variants originate from a homologous recombination event that involving two R09 sites, that was conservative of the proximal block (EXT10). The distal sequence of these sites is highly conserved over about 1000 bp (98 % identity without gap) between EXT2-2 (R09a) and EXT3-2 (R09b)

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