Table 4 tRNA single nucleotide variant analysis
tRNA | Known SNP | CHR | POS | REF | ALT | Control with SNV | Control without SNV | MDS with SNV | MDS without SNV | Fisher p value |
|---|---|---|---|---|---|---|---|---|---|---|
chr13.tRNA1-PheGAA | No | 13 | 95201919 | T | A | 0 | 11 | 4 | 3 | 0.01 |
chr12.tRNA11-PheGAA | No | 12 | 125412404 | T | A | 0 | 16 | 4 | 6 | 0.01 |
chr6.tRNA44-SerAGA | No | 6 | 27446616 | G | A | 0 | 21 | 5 | 13 | 0.01 |
chr6.tRNA46-SerAGA | No | 6 | 27463618 | G | A | 0 | 21 | 5 | 13 | 0.01 |
chr6.tRNA47-SerAGA | No | 6 | 27470843 | G | A | 0 | 21 | 5 | 13 | 0.01 |
chr6.tRNA50-SerAGA | No | 6 | 27500012 | G | A | 0 | 21 | 5 | 13 | 0.01 |
chr6.tRNA51-SerTGA | No | 6 | 27513493 | G | A | 0 | 21 | 5 | 13 | 0.01 |
chr6.tRNA5-SerAGA | No | 6 | 26327842 | G | A | 0 | 21 | 5 | 14 | 0.02 |
chr6.tRNA148-SerTGA | No | 6 | 27473663 | C | T | 0 | 21 | 5 | 14 | 0.02 |
chr6.tRNA147-SerAGA | No | 6 | 27509610 | C | T | 0 | 21 | 5 | 14 | 0.02 |
chr17.tRNA35-SerAGA | No | 17 | 8129984 | C | T | 0 | 21 | 5 | 14 | 0.02 |
chr6.tRNA172-SerTGA | No | 6 | 26312880 | C | T | 0 | 21 | 5 | 15 | 0.02 |
chr7.tRNA21-CysGCA | rs192094984 | 7 | 149112285 | G | A | 0 | 16 | 3 | 7 | 0.05 |
chr8.tRNA11-SerAGA | No | 8 | 96281941 | C | T | 0 | 21 | 5 | 17 | 0.05 |