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Fig. 10 | BMC Genomics

Fig. 10

From: Epigenetic modification with trichostatin A does not correct specific errors of somatic cell nuclear transfer at the transcriptomic level; highlighting the non-random nature of oocyte-mediated reprogramming errors

Fig. 10

Identification of TSA effects on fibroblast gene expression. Protocol used for identifying effects of TSA on the expression profile of a subset of genes that were oppositely expressed between CTR-NT and TSA-NT blastocysts. The altered transcripts in the fibroblasts that had higher normalized expressions toward IVF in CTR-NT rather than TSA-NT blastocysts were classified as corrected transcripts. The influenced transcripts in the fibroblasts that had higher normalized expressions toward IVF in TSA-NT rather than CTR-NT blastocysts were classified as flawed (over-compensated or under-compensated) transcripts

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