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Fig. 1 | BMC Genomics

Fig. 1

From: Complex regulation of ADAR-mediated RNA-editing across tissues

Fig. 1

Experimental design (a) and sequencing processing workflow to call RNA-DNA differences (RDDs) (b). Tissues were harvested from an 8 week old male C57BL/6J mouse. RNA was isolated from 9 tissues and individually used for 100 bp paired-end RNA-sequencing. After alignment to the mm9 genome the number of uniquely mapped reads (umr) was between 28 million and 77 million for each tissue sample. DNA was extracted from the brain and spleen tissues, and sent for 75 bp paired end whole genome sequencing, to average depths of 31X and 23X coverage (586 and 445 million uniquely mapped reads, respectively)

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