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Table 1 Allele based contingency table of one SNP in primary/replication study. Please see the main text for explanation of the notations

From: Power estimation and sample size determination for replication studies of genome-wide association studies

 

Non-effect allele

Effect allele

Total

Control

\(n_{00}^{(j)}\)

\(n_{01}^{(j)}\)

\(2n_{0}^{(j)}\)

Case

\(n_{10}^{(j)}\)

\(n_{11}^{(j)}\)

\(2n_{1}^{(j)}\)

Total

\(n_{00}^{(j)}+n_{10}^{(j)}\)

\(n_{01}^{(j)}+n_{11}^{(j)}\)

2n (j)