Skip to main content
Fig. 3 | BMC Genomics

Fig. 3

From: Multi-omic measurement of mutually exclusive loss-of-function enriches for candidate synthetic lethal gene pairs

Fig. 3

Evaluating toolkit performance with permutation analysis. aThe gene pair outputs of mutually exclusive mutation analysis (MEMU), the expression workflow (BiGEE), and the genomic workflow (BEEM) (with and without discreet copy number calls), are overlapped with the human orthologues of synthetic lethal yeast gene pairs. b In each case, this intersect is compared to 10,000 random samplings of the same size of the gene pair outputs to establish how the workflows perform when compared to chance

Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us