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Fig. 5 | BMC Genomics

Fig. 5

From: Pateamine A-sensitive ribosome profiling reveals the scope of translation in mouse embryonic stem cells

Fig. 5

Translated uORFs in transcripts implicated in stem cell self-renewal and identity. a – d upstream ORFs in CTCF (a) Dicer1 (b) Lin28b (c) and Trim71 (d). The right panels show the footprint profiles for the entire transcripts. On the left, expanded views of the regions flanking uORFs are shown. uORFs are indicated. Different colors indicate different reading frames. Footprint profiles for control (blue) and DMDA-PatA – treated (red) samples are shown. The principal footprint peak(s) are indicated (*). Profiles shown are for ENSMUST00000005841 (CTCF), ENSMUST00000041987 (Dicer1), ENSMUST00000079390 (Lin28b) and ENSMUST00000111816 (Trim71)

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