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Table 2 A summary of 3516 microarray samples and their chemical treatment conditions

From: Fish connectivity mapping: linking chemical stressors by their mechanisms of action-driven transcriptomic profiles

Zebrafish microarray design, sample size, and chemicals

Fathead minnow microarray design, sample size, and chemicals

ZF 21K (Agilent 013223, 15064): USEPA (290)

FHM 15K (Agilent 019597,_036574): USEPA (580)

ethniyl estradiol (EE2)a

bifenthrin (BIF)a

fadrozol (FAD)a

cypermethrin (CYP)a

fipronil (FIP)a

permethrin (PER)a

flutamide (FLU)a

esfenvalerate (ESF)

ketochonazole (KET)a

EE2a

muscimol (MUS)a

Terbufos (TER)a

prochloraz (PRO)a

 

trenbolone (TRB)a

FHM 15K (Agilent 019597): USACE (1711)

trilostane (TRI)a

BPA

vinclozolin (VIN)a

FADa

 

FLUa

ZF 21K (Agilent 013223, 15064): NCBI (154)

Gemfibrozil (GEM)a

tert-Butylhydroquinone (TBHQ)a

KETa

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)a

KET_TNT_KET

oxygen (O2)a

KET_TNT_TNT

2,4-dinitrophenol (DNP)

PRO

1,4-dimethoxybenzene (DMB)

RDX

azinphos-methyl (APM)a

Effluent of Western Lake Superior Sanitary District (WLSSD)

Haloperidol (HAL)

TRB a

 

TRB_BPA_TRB_BPA

ZF 43K (Agilent 019161): USEPA (24)

TRB_BPA_BPA

FLUa

TRB_BPA_TRB

PROa

TRB_EE2_EE2

 

TRB_EE2_TRB

ZF 43K (Agilent 019161): NCBI (270)

TRB_EE2_TRB_EE2

benz(a)anthracene (BAA)a

TRB_TCC_TCC (triclocarban)

decabromodiphenyl ether (BDE)a

TRB_TCC_TRB

bisphenol A (BPA)a

TRB_TCC_TRB_TCC

dibenzothiophene (DBT)

TRIa

Diazepam (DIA)a

VINa

17ß-estradiol (E2)a

 

E2 a

FHM 15K (Agilent 019597_036574): NCBI (487)

EE2a

Diethylstilbestrol (DES)a

FLU

Dihydrotestosterone (DHT)

genistein (GEN)a

E2a

Linuron (LIN)a

Field exposure (EFFLa, EFFHaa; effluent, WWTP San Diego; EFFHba; effluent, WWTP Los Angeles)

methylparaben (MPA)a

Field exposure (surface, stream, waste watera)

protein kinase C inhibitor 412 (PKC412)a

Field exposure (liver: ElyUSa, ElyEFFa, ElyDSa, HutUS, HutEFFa, HutDSa, RochUSa, RochEFFa, RochDSa))

Propanil (PPL)a

Field exposure (ovary: ELYeff, ELYds, HUTeff, HUTds, ROCHds, ROCHeff)

PROa

FLU

Pyrene (PYR)

Linuron

cyclotrimethylenetrinitramine (RDX)a

perflorinated chemicals (PFC)

 

Phenanthrene (PHE)a

 

Progesterone (PGST)

 

Propranolol (PPLL)

 

RDX

  1. Zebrafish: ZF 21K (Agilent 013223, 21495 probes unique; Agilent 015064, 21495 probes), ZF 43K (Agilent 019161, 43603 probes unique). Fathead minnow: FHM 15K (Agilent 019597, 15208 unique probes; Agilent 036574, 15208 of 49849 unique probes). Chemicals with at least one experiment condition (different exposure durations either in single or combinations) with DEGs ≥ 4 are marked by “a”, and those shared across platforms or species are highlighted once in bold