Skip to main content
Fig. 3 | BMC Genomics

Fig. 3

From: Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study

Fig. 3

The top 21 most commonly reported a-CpGs and their direction of association with aging. The top 21 a-CpGs were selected with following criteria: the a-CpG was identified in present study and in the V90+ study, as well as in two or more other studies (Hannum et al. [13], Garagnani et al. [12] or Florath et al. [23]); the sites were reported as aging-associated in blood samples and the data were obtained using 450 BeadChip technology. Methylation level differences in YFS between the highest and the lowest age groups (between 40- and 49-year-old individuals; calculated from the medians of residuals after adjusting for effects of sex and cell type proportions), are illustrated as bars. The bars are colored according to the hypomethylation or hypermethylation status (grey = hypomethylated, black = hypermethylated). Gene annotation is shown for each bar, where applicable (na = no gene annotation). The corresponding data is presented in Additional file 3: Table S4

Back to article page