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Table 4 GO function terms were enriched within genes with hypermethylated a-CpGs in the analysis with GOrilla. Table contains the full list of enriched GO function terms (Bonferroni-adjusted p < 0.05) obtained from analysis with GOrilla [21, 43]

From: Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study

GO term

Description of the function

p-value (-log10)

GO:0043565

Sequence-specific DNA binding

10.001

GO:0000981

Sequence-specific DNA binding RNA polymerase II transcription factor activity

7.322

GO:0001071

Nucleic acid binding transcription factor activity

6.721

GO:0003700

Sequence-specific DNA binding transcription factor activity

6.721

GO:0003677

DNA binding

6.625

GO:0005326

Neurotransmitter transporter activity

5.148

GO:0005488

Binding

4.967