From: Nonlinear transcriptomic response to dietary fat intake in the small intestine of C57BL/6J mice
Section and Responses | GO ID | GOBP | Proximal | Middle | Distal | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Set Size | Hits | Adjusted p-value | Set Size | Hits | Adjusted p-value | Set Size | Hits | Adjusted p-value | |||
Prox-Mid-Dist (all linear) | GO:0006953 | Acute-phase response | 22 | 5 | 0.09 | 22 | 6 | 0.08 | 21 | 3 | 0.03 |
Prox-Mid (lm - lm) | GO:0006629 | Lipid metabolic process | 184 | 33 | <0.01 | 183 | 46 | <0.01 | Â | Â | Â |
GO:0006631 | Fatty acid metabolic process | 68 | 19 | <0.01 | 67 | 28 | <0.01 | Â | Â | Â | |
GO:0006635 | Fatty acid beta-oxidation | 21 | 9 | <0.01 | 21 | 11 | <0.01 | Â | Â | Â | |
GO:0006637 | Acyl-CoA metabolic process | 19 | 7 | <0.01 | 19 | 6 | 0.04 | Â | Â | Â | |
GO:0007040 | Lysosome organization | 18 | 5 | 0.03 | 18 | 6 | 0.04 | Â | Â | Â | |
GO:0015031 | Protein transport | 386 | 45 | 0.01 | 387 | 60 | <0.01 | Â | Â | Â | |
GO:0022900 | Electron transport chain | 69 | 14 | <0.01 | 69 | 18 | <0.01 | Â | Â | Â | |
GO:0055085 | Transmembrane transport | 390 | 42 | 0.07 | 391 | 57 | 0.02 | Â | Â | Â | |
Prox-Mid (lm - log) | GO:0042632 | Cholesterol homeostasis | 33 | 11 | <0.01 | 33 | 4 | 0.10 | Â | Â | Â |
Prox-Mid (lm - exp) | GO:0030301 | Cholesterol transport | 15 | 7 | <0.01 | 15 | 4 | 0.03 | Â | Â | Â |
Mid-Dist (lm - lm) | GO:0006520 | Cellular amino acid metabolic process | Â | Â | Â | 16 | 5 | 0.07 | 16 | 2 | 0.05 |
GO:0016042 | Lipid catabolic process | Â | Â | Â | 69 | 14 | 0.05 | 69 | 5 | 0.03 | |
GO:0051262 | Protein tetramerization | Â | Â | Â | 17 | 5 | 0.09 | 17 | 2 | 0.05 | |
Mid-Dist (lm - exp) | GO:0043154 | Negative regulation of caspase activity | Â | Â | Â | 36 | 10 | 0.02 | 36 | 2 | 0.06 |
Mid-Dist (log - lm) | GO:0006644 | Phospholipid metabolic process | Â | Â | Â | 17 | 4 | 0.01 | 17 | 2 | 0.05 |
GO:0006749 | Glutathione metabolic process | Â | Â | Â | 24 | 4 | 0.04 | 24 | 2 | 0.08 | |
GO:0045859 | Regulation of protein kinase activity | Â | Â | Â | 16 | 4 | 0.01 | 16 | 2 | 0.05 |