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Fig. 6 | BMC Genomics

Fig. 6

From: Genome-wide studies reveal novel and distinct biological pathways regulated by SIN3 isoforms

Fig. 6

SIN3 187 distinctly regulates differentiation related genes. a Average ChIP signal of SIN3 187HA over the genes directly regulated by SIN3 187. b qRT-PCR verification of genes identified by RNA-seq to change in expression after overexpression of SIN3 187 versus control (left) but not affected upon Sin3A knockdown versus GFP RNAi (right). P-value * <0.05, *** <0.0001. c Gene ontology analysis of the Class C genes identified in Fig. 5 are represented as bar plots. The Y-axis lists the broad GO categories. Red: categories of genes that are directly repressed. Blue: categories of genes that are directly activated. P-value (gene ontology categories) <0.05. Biological processes labelled in bold indicate the unique processes that are overrepresented for genes distinctly regulated by SIN3 187

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