BMC Genomics

Table 1 Population estimates of mutation rates (θ) and recombination rates (ρ) per base

From: Genome-wide mosaicism within Mycobacterium abscessus: evolutionary and epidemiological implications

	θ				ρ				r / μ
	M. abs	M. bol	M. mas	MAB	M. abs	M. bol	M. mas	MAB	M. abs	M. bol	M. mas	MAB
argH	0.007	0.006	0.015	0.018	0.005	0	0	0.001	0.714	0	0	0.056
cya	0.001	0.012	0.011	0.012	0.004	0.016^a	0.004	0.008^a	4	1.333^a	0.364	0.667^a
glpK	0.007	0.008	0.006	0.01	0.002	0.011	0.001	0.004	0.286	1.375	0.167	0.4
gnd	0.004	0.012	0.014	0.016	0.005	0	0.006	0.004^a	1.25	0	0.429	0.25^a
murC	0.009	0.012	0.008	0.015	0	0	0.001	0	0	0	0.125	0
pta	0.009	0.006	0.008	0.01	0.016^a	0	0.012^a	0.006	1.778	0	1.5	0.6
purH	0.011	0.003	0.011	0.012	0.007^a	0.008^a	0.005^a	0.005	0.636	2.667	0.455	0.417^a
Average.	0.007	0.008	0.01	0.013	0.006	0.005	0.004	0.004	0.813	0.593	0.397	0.29
Concat^.b	0.008	0.008	0.011	0.013	0.041^c	0.009	0.03 ^c	0.004	5.125^a	1.125 ^a	2.727^a	0.308^a
CI 95 %					0.038–0.044	0.008–0.010	0.028–0.032	0.004–0.004	4.75–5.5	1–1.25	2.55–2.9	0.308–0.308

The analyses are realised within lineages and for the MAB complex (pooled genotypes)
Values for rho (ρ) were obtained by dividing the per-locus recombination rate estimate from LDhat by the sequence length. μ: mutation rate per nucleotide; r: recombination rate per nucleotide. ^a: significant recombination estimates. Concat. ^bconcatenated data set. ^c: recombination significantly higher than intra-genic recombination rates (^a and ^c: 95 % confidence interval)

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ISSN: 1471-2164

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