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Fig. 2 | BMC Genomics

Fig. 2

From: Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice

Fig. 2

Sex-specific differences in mean time to death at different doses of influenza A H3N2 virus infection in C57BL/6J, NOD/ShiLtJ and WSB/EiJ. The same data set and color code as in Fig. 1 was used to analyze mean time to death (MTTD) of the strains (clear bars: female; dashed bars: male mice). Changes in MTTD were calculated for 14 days p.i., survival was scored as an MTTD value of 15. Significant sex-specific differences were calculated for infection with 1 × 101 FFU (a) and 2x103 FFU (b). NOD/ShiLtJ and WSB/EiJ exhibited significant sex-specific differences in infections with 1 × 101 FFU and C57BL/6J in infections with 2 × 103 FFU. The dashed line marks the end of experiment. Significances were calculated using Mann Whitney U test and are marked by stars (*: p < 0.1; **: p < 0.01)

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BMC Genomics

ISSN: 1471-2164

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