Table 3 Transcripts with putative functions (GO terms) related to immune effectors that were differentially expressed during M. mercenaria focal response against QPX. Additional information on these transcripts is given in Additional file 2. “Inf” designates an infinite fold change calculated for focal response as the expression of that transcript in non-nodule tissue was equal to 0
From: Clam focal and systemic immune responses to QPX infection revealed by RNA-seq technology
Transcripts ID | Annotation | Regula-tion | Fold change | Function/GOs |
|---|---|---|---|---|
Oxidation-reduction processes | ||||
comp186178_c0_seq12 | dual oxidase | Up | Inf | P:response to oxidative stress; P:oxidation-reduction process; F:peroxidase activity |
comp185478_c0_seq4 | allene oxide synthase-lipoxygenase protein | Up | 10.0 | P:oxidation-reduction process; F:oxidoreductase activity; F:metal ion binding; |
comp186926_c0_seq7 | c-terminal-binding protein | Up | Inf | P:oxidation-reduction process; F:NAD binding; |
comp187462_c1_seq6 | chorion peroxidase | Up | 11.8 | P:oxidation-reduction process; P:response to oxidative stress; F:peroxidase activity |
comp157634_c0_seq8 | cytochrome p450 | Up | 178.6 | P:oxidation-reduction process; F:oxidoreductase activity; F:iron ion binding |
comp183426_c1_seq2 | dbh-like monooxygenase protein 1-like protein | Up | 24.8 | P:oxidation-reduction process; F:dopamine beta-monooxygenase activity; F:oxidoreductase activity |
comp188723_c0_seq1 | isocitrate dehydrogenase | Up | Inf | P:oxidation-reduction process; F:magnesium ion binding; F:NAD binding |
comp169486_c0_seq1 | lysyl oxidase-like protein 2 | Up | 22.5 | F:oxidoreductase activity; P:oxidation-reduction process; F:scavenger receptor activity |
comp192316_c0_seq4 | methylenetetrahydrofolate reductase | Up | Inf | P:oxidation-reduction process; F:methylenetetrahydrofolate reductase (NADPH) activity; |
comp189621_c0_seq4 | procollagen-oxoglutarate 5-dioxygenase 3 | Up | 9.7 | P:oxidation-reduction process; F:iron ion binding |
comp185148_c0_seq6 | ww domain-containing oxidoreductase | Up | Inf | F:oxidoreductase activity; P:metabolic process |
Protease | ||||
comp184786_c1_seq4 | fur protein precursor | Up | Inf | F:serine-type endopeptidase activity |
comp180950_c0_seq5 | lysosomal protective protein precursor | Up | 47.1 | F:serine-type carboxypeptidase activity |
comp180950_c0_seq2 | lysosomal protective protein precursor | Up | 26.9 | F:serine-type carboxypeptidase activity |
comp189961_c0_seq12 | N-acetylated-alpha-linked acidic dipeptidase 2 | Up | 16.3 | F:metallopeptidase activity; |
comp178551_c1_seq1 | membrane metallo-endopeptidase-like 1-like | Up | Inf | F:metalloendopeptidase activity; |
comp184011_c0_seq4 | blastula protease 10 | Up | 8.1 | F:metalloendopeptidase activity; |
comp191868_c1_seq1 | matrix metalloproteinase-19 | Up | 59.1 | - |
comp174947_c0_seq3 | isoaspartyl peptidase l-asparaginase-like | Up | Inf | F:hydrolase activity |
comp183848_c0_seq3 | kyphoscoliosis peptidase | Down | −8.7 | P:microtubule-based movement |
comp188831_c0_seq3 | puromycin-sensitive aminopeptidase-like isoform | Down | −65.5 | F:metallopeptidase activity; |
comp191458_c3_seq5 | aspartic protease with reverse transcriptase activity | Down | −245.4 | F:aspartic-type endopeptidase activity; |
Protease inhibitor | ||||
comp189919_c1_seq4 | alpha macroglobulin | Up | 21.9 | F:endopeptidase inhibitor activity |
comp189919_c1_seq2 | alpha macroglobulin | Up | 12.4 | F:endopeptidase inhibitor activity |
comp181286_c4_seq1 | thioester-containing protein | Up | 10.2 | F:endopeptidase inhibitor activity |
comp191416_c1_seq2 | thioester-containing protein-a | Up | 14.8 | F:endopeptidase inhibitor activity |
comp191416_c1_seq1 | thioester-containing protein-b | Up | 9.5 | F:endopeptidase inhibitor activity |
comp192366_c0_seq1 | thioester-containing protein-c | Up | 32.5 | F:endopeptidase inhibitor activity |
comp191416_c0_seq5 | thioester-containing protein-e | Up | 12.9 | F:endopeptidase inhibitor activity |
comp191416_c0_seq4 | thioester-containing protein-e | Up | 22.4 | F:endopeptidase inhibitor activity |
Ion transporter and sequester | ||||
comp190604_c1_seq1 | ceruloplasmin precursor | Up | 21.8 | P:copper ion transport; P:cellular iron ion homeostasis; F:ferroxidase activity |
comp182612_c1_seq1 | ferric-chelate reductase 1 | Up | 16.7 | Iron transfer |
comp180332_c1_seq1 | ferric-chelate reductase 1-like | Up | 11.8 | Iron transfer |
comp177359_c0_seq1 | selenium binding protein | Down | −11.0 | P:protein transport; F:selenium binding |
comp174164_c0_seq20 | divalent metal transporter | Up | 328.2 | P:transport; F:transporter activity |
Wound repair | ||||
comp185425_c1_seq1 | actin-related protein 2 3 complex subunit 5-like | Up | Inf | C:cytoskeleton; P:regulation of actin filament polymerization |
comp93954_c0_seq1 | extracellular matrix protein 2 isoform1 | Up | 25.9 | F:protein binding |
comp188753_c5_seq1 | cartilage matrix protein | Up | 25.8 | F:chitin binding; P:chitin metabolic process; C:extracellular region |
comp142858_c0_seq1 | epidermal growth factor-like protein 8-like | Up | 18.5 | F:protein binding; F:calcium ion binding |
comp192650_c1_seq4 | multiple epidermal growth factor-like domains 6 | Up | 21.9 | F:protein binding |
comp186665_c0_seq1 | thrombospondin- partial | Up | 106.9 | F:protein binding |
comp186665_c0_seq4 | thrombospondin- partial | Up | 38.0 | F:protein binding |
comp184960_c0_seq4 | septin-7-like isoform 8 | Up | Inf | P:cell cycle; F:GTP binding; C:septin complex |
comp184960_c0_seq42 | septin-7-like isoform 6 | Up | 8.9 | - |