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Table 5 Selected transcripts with annotated functions (GO terms) related to immune response that were differentially expressed in naïve M. mercenaria as compared to QPX infected individuals. Additional information on these transcripts is given in Additional file 4. “Inf” designates an infinite fold change calculated for focal response as the expression of that transcript in non-nodule tissue was equal to 0

From: Clam focal and systemic immune responses to QPX infection revealed by RNA-seq technology

Transcripts ID

Annotation

Fold change

Function/GOs

Over-expressed

comp168250_c0_seq2

macrophage expressed protein

84.0

-

comp160023_c0_seq1

serine protease inhibitor 1

18.1

F:protein binding

comp117137_c0_seq1

proline-rich transmembrane protein 1

148.6

P:response to biotic stimulus

comp134883_c0_seq1

c-type lectin domain family 10 member a-like

121.4

F:carbohydrate binding

comp180146_c3_seq31

aplysianin a precursor

Inf

P:defense response; F:oxidoreductase activity

comp179365_c0_seq7

insulin-related peptide receptor

20.0

F:scavenger receptor activity

comp187368_c2_seq9

apoptosis 1 inhibitor

16.2

P:apoptotic process;

comp193015_c0_seq1

baculoviral iap repeat-containing protein 4

391.0

P:negative regulation of apoptotic process; F:ubiquitin-protein ligase activity

Under-expressed

comp39934_c1_seq1

heat shock 70 kda protein

Inf

P:response to stress

comp192296_c2_seq3

usp-like protein isoform 2

−46.2

P:response to stress

comp169961_c0_seq2

cytochrome p450 1a1

−75.1

-

comp176418_c0_seq1

isoaspartyl peptidase l-asparaginase-like

−8.0

F:hydrolase activity

comp191987_c0_seq10

macrophage mannose receptor 1-like

−7.8

F:carbohydrate binding

comp186563_c0_seq7

bile salt-activated lipase-like

−9.8

F:hydrolase activity