Fig. 2
From: Shared genetic control of expression and methylation in peripheral blood
Effect of the adjustment for blood cellular composition on the correlation between expression and methylation. Pearson correlation between gene expression and DNA methylation before (x-axis) and after (y-axis) correction for observed blood cell composition. Probe pairs that passed Bonferroni correction and had a correlation coefficient of |ρ|≥0.5 before adjustment for cellular composition were selected. The probe pairs are split by the relative chromosomal position of the probes in a given pair. The correlations are unchanged after the correction for a small proportion of probe pairs located on the same chromosome. However, the majority of the correlations shifted towards zero. The red line is an identity line