Fig. 4

Two-dimensional bit-score plots between CMV strains. Graph represents comparisons of gene homologue bit-scores across CyCMV Mauritius versus CyCMV Ottawa and RhCMV 68–1 versus RhCMV 180.92. Bit-score among RhCMV homologues of the indicated gene are tracked on the y-axis while CyCMV homologues are tracked on the x-axis. A high bit-score indicated a high level of similarity between genes, while a bit-score of zero indicates one or both species in the comparison lacked a copy of the gene. Genes that fall on the diagonal are equally conserved in all comparisons, for example CyUL48 (rh78) and CyUL74 (rh74); genes that fall to one side of the diagonal are better conserved between viruses of one species than between viruses of the other species, for example COX-2 (rh10) which is highly conserved between RhCMV 180.92 and RhCMV 68–1, but absent from CyCMV Ottawa, and CyUL94 (rh129). Genes are coloured according to known gene family. Select genes are annotated according to their CyCMV Mauritius names. Where genes belong to multiple families only one is indicated, for breakdown of chart by gene family see Additional file 8: Figure S7 or Additional file 9: Figure S8, Additional file 10: Figure S9 and Additional file 11: Figure S10 for alternative pairwise comparisons