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Table 2 Detailed information for the most widely present homologous gene clusters

From: Comparative genomics reveals multiple pathways to mutualism for tick-borne pathogens

Cluster #

Representative protein accession #

# of organisms in cluster

Product description

KEGG EC #

30

AAV86731

38

2,3-bisphosphoglycerate-independent phosphoglycerol mutase

5.4.2.12

30

AAV87091

38

nicotinate-nucleotide pyrophosphorylase

2.4.2.19

30

AAV87100

38

quinolinate synthetase A

2.5.1.72

29

NP_212375

35

glycerol kinase

2.7.1.30

28

AAV86691

33

1-deoxy-D-xylulose-5-phosphate reductoisomerase

1.1.1.267

28

AAV87137

33

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

4.6.1.12

27

AHX03201

32

tRNA threonylcarbamoyladenosine biosynthesis protein TsaE

no EC number

26

NP_212377

30

glycerol-3-phosphate dehydrogenase

1.1.5.3

25

AAV87130

25

hypothetical

no entry

25

NP_359873

25

hypothetical

no entry

25

AAV86484

25

pyridoxine 5-phosphate synthase

2.6.99.2

25

AAV86592

25

bifunctional proline dehydrogenase, pyrroline-5-carboxylate dehydrogenase

1.5.5.2, 1.2.1.88

25

AAV86778

25

thiamine biosynthesis oxidoreductase

1.4.3.19

24

NP_359861

24

divalent cation tolerance protein

no entry

24

NP_360910

24

hypothetical

no entry

24

NP_360096

24

hypothetical

no entry

23

NP_360134

23

hypothetical

no entry

23

NP_360791

23

hypothetical

no entry

22

YP_001499275

22

AbrB family transcriptional regulator

no entry

22

NP_360166

22

cell filamentation protein Fica

no entry

22

NP_360392

22

hypothetical

no entry

22

NP_360955

22

plasmid stability protein

no entry

21

NP_359844

21

hypothetical

no entry

21

NP_360418

21

biotin-protein ligase

no entry

21

NP_360956

21

hypothetical

no entry

  1. aThis gene was reported as one of three representative ORGs, RiOG_1005, i.e., present in all tick-borne Rickettsial genomes in the study by Gillespie et al. [27]