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Table 3 Comparison of lowest-cost on →off path across H-Ras WT and variants

From: Computing energy landscape maps and structural excursions of proteins

Sequence

m a x_n n_d i s t (Ã…)

Path cost (REU)

Highest Energy (REU)

Nr. Edges

WT

1.45/10

266

–251

90

 

1.45/7.5

108

–299

56

G12S

1.45/10

—

—

—

 

1.45/ /7.5

130

–230

26

G12C

1.45/10

—

—

—

 

1.45/ /7.5

232

–150

66

G12D

1.45/10

—

—

—

 

1.45/ /7.5

119

–277

51

G12V

1.45/10

—

—

—

 

1.45/ /7.5

109

–276

72

Q61L

1.45/10

—

—

—

 

1.45/ /7.5

85

–263

62

Y32CC118S

1.45/10

—

—

—

 

1.45/ /7.5

131

–265

54

R164AQ165V

1.45/10

—

 

—

 

1.45/ /7.5

131

–277

72