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Fig. 5 | BMC Genomics

Fig. 5

From: Regulatory complexity revealed by integrated cytological and RNA-seq analyses of meiotic substages in mouse spermatocytes

Fig. 5

Regulation of substage-concordant gene expression during meiotic prophase. Analyses suggest that substage-concordant gene expression is regulated both positively and negatively by a network of TFs. TFs are shown by their gene names, and the meiotic substages of predicted TF target genes are shown in the center. Black arrows represent a TF acting as an enhancer on its target genes and red bars represent a TF acting as a suppressor on its target genes. (Abbreviations: PL = pre-leptonema, EL = early leptonema, LL/Z = late leptonema and zygonema, LL/Z/EP = late leptonema, zygonema, and early pachynema, EP = early pachynema, EP/LP/D = early and late pachynema and diplonema), LP/D = late pachynema and diplonema, Anti-EL = genes negatively concordant with early leptonema, Anti-LL/Z/EP = genes negatively concordant with late leptonema, zygonema, and early pachynema)

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