Table 1 Expression (in rpm) of pairs of highly expressed miRNAs/5’isomiRs in a panel of breast cancer cell lines
Notation of isoform | Seed sequence | MCF7 | MDA-MB-231 | T47D | BT20 | BT474 | MDA-MB-468 | ZR-75 | MCF10A | |
|---|---|---|---|---|---|---|---|---|---|---|
miR-10a-5p 0|x | canonical | ACCCTGT | 81.9 | 4923.9 | 9254.5 | 7698.9 | 96.5 | 181.4 | 854.1 | 582.7 |
miR-10a-5p +1|x | isomiR | CCCTGTA | 56.9 | 2158.4 | 3911.3 | 3660.0 | 64.2 | 65.0 | 477.0 | 273.0 |
miR-1307-3p 0|x | canonical | CTCGGCG | 1159.2 | 737.2 | 2299.7 | 575.6 | 1894.2 | 554.8 | 2560.7 | 290.0 |
miR-1307-3p +1|x | isomiR | TCGGCGT | 394.2 | 253.2 | 943.8 | 222.5 | 643.7 | 348.3 | 784.3 | 72.7 |
miR-140-3p 0|x | canonical | ACCACAG | 180.9 | 486.8 | 117.4 | 289.0 | 149.1 | 63.0 | 181.2 | 199.2 |
miR-140-3p +1|x | isomiR | CCACAGG | 407.7 | 851.6 | 284.8 | 568.7 | 217.6 | 95.2 | 306.2 | 332.8 |
miR-183-5p 0|x | canonical | ATGGCAC | 1187.2 | 91.7 | 1065.9 | 1132.5 | 2017.2 | 1028.1 | 849.9 | 518.7 |
miR-183-5p +1|x | isomiR | TGGCACT | 1102.0 | 44.0 | 831.3 | 822.5 | 1860.5 | 767.9 | 725.6 | 312.4 |
miR-203-3p 0|x | canonical | TGAAATG | 2327.2 | 3.1 | 2514.6 | 544.1 | 5319.0 | 427.8 | 2870.3 | 71.3 |
miR-203-3p +1|x | isomiR | GAAATGT | 2115.5 | 1.5 | 1137.8 | 329.8 | 2116.1 | 175.1 | 1104.8 | 23.1 |
miR-30a-3p 0|x | canonical | TTTCAGT | 13.9 | 991.7 | 162.5 | 191.8 | 30.8 | 1033.2 | 108.8 | 239.7 |
miR-30a-3p +1|x | isomiR | TTCAGTC | 3.7 | 305.1 | 53.5 | 65.8 | 6.6 | 311.7 | 35.8 | 44.1 |