Table 2 Enrichment analysis of the maximally functional module in rifampin
DAVID (Term) | Genes | P-value |
|---|---|---|
GO: Response to drug | ABCB1,UGT1A4,CAV1,CAV2 | 3.6E-2 |
KEGG: Metabolism of xenobiotics by cytochrome P450 | UGT1A4,ADH6,CYP1A1,CYP2C19,CYP2C9,CYP2E1 | 2.0E-4 |
KEGG: Retinol metabolism | UGT1A4,ADH6,CYP1A1,CYP2C19,CYP2C9 | 1.4E-3 |
KEGG: Drug metabolism | UGT1A4,ADH6, CYP2C19,CYP2C9,CYP2E1 | 2.4E-3 |
KEGG: Linoleic acid metabolism | CYP2C19,CYP2C9,CYP2E1 | 2.7E-2 |
KEGG: Pathways in cancer | CEBPA,CREBBP,SMAD3,TRAF2,BIRC3,EGLN2,FN1,IKBKG | 2.9E-2 |
Focal adhesion | BIRC3,CAV1,CAV2,FN1,ITGA1,THBS1 | 3.7E-2 |