Identification of combinatorial host-specific signatures with a potential to affect host adaptation in influenza A H1N1 and H3N2 subtypes

Table 1 The training data

	Nr. of sequences for each subtype					Features after MCFS
	H1N1		H3N2			Features after MCFS
Protein	Avian	Human	Avian	Human	Total features	H1N1	H3N2
HA	214	5205	164	3715	628	115	88
NA	205	3093	173	3412	517	93	79
NS1	150	1258	150	1176	249	98	85
NEP	61	407	54	299	124	31	26
NP	125	839	93	773	506	61	69
M1	45	467	42	355	275	18	15
M2	65	461	64	503	98	25	23
PA	192	1677	143	1358	726	65	47
PA-X	57	164	45	244	252	28	24
PB1	171	1654	132	1347	762	59	33
PB2	184	1817	136	1297	776	52	42
PB1-F2	151	224	112	737	101	64	54

Total Features are the total number of aa positions that are investigated. Features after MCFS are the aa positions that are ranked significant, i.e. having power to discriminate avian from human sequences

ISSN: 1471-2164