Fig. 2From: Orthologs, turn-over, and remolding of tRNAs in primates and fruit fliesStepwise refinement of the candidate graph Γ c . a The graph Γ c represents the possible orthology assignments among tRNA loci derived from the synteny anchors. Only genes from different species can be orthologs, hence no edges connect loci in the same species. b Based on sequence similarity edges are removed between tRNAs from different isoacceptor families. c A modified Needleman-Wunsch alignment algorithm is used to identify order-preserving subgroups. This step admits local tandem duplications but not duplications of larger subclustersBack to article page