Table 1 Features of nHKGs and tHKGs
From: A strategy to identify housekeeping genes suitable for analysis in breast cancer diseases
Uniprotkb | Protein name | Gene | Mean | CV (%) | Biological process |
|---|---|---|---|---|---|
nHKGs | |||||
Q92575 | UBX domain-containing protein 4 | UBXN4 | 81.75 | 11.45 | Response to unfolded protein |
Q08211 | ATP-dependent RNA helicase A | DHX9 | 158.25 | 12.42 | ATP catabolic process, DNA duplex unwinding |
P17152 | Transmembrane protein 11, mitochondrial | TMEM11 | 68.12 | 12.83 | Mitochondrion organization |
Q6PKG0 | La-related protein 1 | LARP1 | 137.87 | 13.10 | Cell proliferation |
Q13190 | Syntaxin-5 | STX5 | 65.37 | 13.33 | Vesicle transport |
O75179 | Ankyrin repeat domain-containing protein 17 | ANKRD17 | 33.62 | 14.03 | Blood vessel maturation |
Q92797 | Symplekin | SYMPK | 60.75 | 14.29 | Cell adhesion |
Q6P1X5 | Transcription initiation factor TFIID subunit 2 | TAF2 | 23.87 | 14.41 | G2/M transition of mitotic cell cycle |
Q9H7U1 | Serine-rich coiled-coil domain-containing protein 2 | CCSER2 | 20.00 | 15.12 | Microtubule bundle formation |
Q6NZ67 | Mitotic-spindle organizing protein 2B | MZT2B | 179.62 | 15.69 | – |
tHKGs | |||||
Q14671 | Pumilio homolog 1 | PUM1 | 45.50 | 24.56 | Vesicle-transport, translation |
P40429 | 60S ribosomal protein L13a | RPL13A | 3028.62 | 25.51 | Translation |
P00558 | Phosphoglycerate kinase 1 | PGK1 | 488.37 | 30.91 | Glycolysis |
P08236 | Beta-glucuronidase | GUSB | 70.00 | 36.56 | Metabolic processes |
P60709 | Actin, cytoplasmic 1 | ACTB | 9500.25 | 37.06 | Protein folding, chromatin remodeling |
Q9UNQ2 | Probable dimethyladenosine transferase | DIMT1 | 26.62 | 41.82 | rRNA processing |
Q71U36 | Tubulin alpha-1A chain | TUBA1A | 658.00 | 47.50 | Protein folding, G2/M transition of cell cycle |
P04406 | Glyceraldehyde-3-phosphate dehydrogenase | GAPDH | 3580.12 | 66.79 | Metabolic process, protein folding |
P61769 | Beta-2-microglobulin | B2M | 1530.12 | 93.47 | Immunity |