Fig. 4

Whole proteome pair-wise comparisons of A. baumannii strains. The names of strains along with the number of proteins and protein families are mentioned along each side of the matrix. Each box in the matrix depicts the fractions of shared proteins between the two corresponding strains. The homology between the proteomes is depicted in green color (dark green color represents more homology between proteomes). The number and percentage of shared proteome is also shown in the corresponding box of the matrix. The last row in the matrix depicts the homology within the proteomes and indicated as internal homologies in individual strain (genome/proteome) and are shaded in red color, the scale given showed 2.9 % least to 7.0 % the highest). Two homology blocks (marked in figure as red and blue color) shaded dark green suggest strong homology among the strains. Strains in red and blue block belong to international clone I and II, respectively. The blue block showed homology of more than 80 % between strains A. baumannii TCDC and A. baumannii 1656-2 with A. baumannii BJAB7104, MDR-TJ, MDR-Z, TYTH and AC30. Similarly, in red block three strains (A. baumannii AYE, AB0057, AB307-0294) showed more than 83 % homology with A. baumannii A1 and A. baumannii AB5075. Highest internal homology within proteome was seen in A. baumannii strain TCDC and A. baumannii AB030 i.e., 7 % and 6.7 % respectively. The matrix results are comparable to pan-core dendogram. Pancore dendrogram is based upon the shared gene families among the strains. IC I and II strains in the red and blue blocks in the matrix, respectively, make separate clads in the tree, indicating the phylogenetic correlation of the strains