Fig. 5

Categorization of core proteome of A. baumannii. Illustration of possible correlations between different parameters for the prioritization of core proteome of A. baumannii strains. a Depicts the generation of the prioritized proteins among the core proteins, selected on the basis of sub-cellular localization, virulence, essentiality and non-host homologs. Core proteins are represented in green circle of the Venn diagram, non-host homologs proteins in blue, essential proteins in purple, virulent proteins in light blue and secreted proteins in red color. The numbers presented in the overlapping regions of the circles show the number of strains exhibiting a particular set of category. 13 proteins among the core proteins have been prioritized, as they simultaneously share all four properties (secreted, essential, virulent, non-host homologs). The proteins satisfying all these criteria were taken into consideration for further epitope mapping approaches. b Demonstrates the individual categories i.e., core proteins (green bar, 2,445 proteins), non-host homologs proteins (blue bar, 2,131), essential proteins (purple bar, 956), virulent proteins (light blue bar, 295), and secreted proteins (red bar, 19). c Depicts the number of proteins sharing the specific number of attributes (essentiality, virulent, sub-cellular localization, non-host homologs). The scale shifts from dark purple color (1 list) to light color (2, 3, 4 lists)