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Fig. 7 | BMC Genomics

Fig. 7

From: The Rat microRNA body atlas; Evaluation of the microRNA content of rat organs through deep sequencing and characterization of pancreas enriched miRNAs as biomarkers of pancreatic toxicity in the rat and dog

Fig. 7

Clinical chemistry and serum miRNA analysis of caerulein treated rats. Rats treated with 0, 15 and 50ug/kg of caerulein were examined for clinical chemistry and miRNA changes (doses are indicated by red, green and blue respectively). Time is indicated on the x-axis and the log 2 of the fold change, the mean as well as 95 % confidence interval are indicated on the y-axis. miRNAs were incereased in the serum of rats with 15 and 50 ug/kg of caerulein coincident with increases in amylase and lipase with maximal increases occurring at 8–24 h for miRs-216a-5p, 217-5p and 375-3p. Values are normalized to vehicle and to the cel-miR-55-3p spike in

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BMC Genomics

ISSN: 1471-2164

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