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Table 4 Top 20 functional categories of predicted gene targets by uniquely expressed miRNAs in sera and exosomes

From: Comparative miRNAome analysis revealed different miRNA expression profiles in bovine sera and exosomes

Sera

Exosomes

Category

B-H p-value

Category

B-H p-value

Cellular Growth and Proliferation

1.27E-28-1.11E-03

Cellular Growth and Proliferation

2.76E-12-6.05E-02

Cancer

4.54E-24-1.01E-03

Cancer

1.26E-08-6.05E-02

Organismal Injury and Abnormalities

4.54E-24-1.11E-03

Organismal Injury and Abnormalities

1.26E-08-6.05E-02

Cell Death and Survival

5.07E-24-1.01E-03

Cell Morphology

1.67E-08-6.05E-02

Organismal Survival

5.07E-24-2.65E-06

Organismal Survival

3.05E-08-2.39E-02

Cellular Assembly and Organization

7.61E-20-4.99E-04

Cellular Assembly and Organization

6.75E-07-6.05E-02

Cellular Function and Maintenance

7.61E-20-8.07E-04

Cellular Function and Maintenance

6.75E-07-6.05E-02

Cell Morphology

8.22E-19-7.27E-04

Cellular Movement

3.04E-06-6.03E-02

Molecular Transport

2.63E-16-9.67E-04

Cell Death and Survival

3.43E-06-6.03E-02

Cellular Movement

2.28E-15-1.05E-03

Gastrointestinal Disease

6.85E-06-6.03E-02

Cellular Development

4.18E-15-1.09E-03

Cardiovascular System Development and Function

8.40E-06-6.03E-02

Neurological Disease

3.21E-13-1.11E-03

Molecular Transport

9.36E-06-6.04E-02

Gene Expression

3.57E-13-3.95E-04

Cellular Development

9.36E-06-5.83E-02

Cardiovascular System Development and Function

3.57E-13-1.13E-03

Connective Tissue Development and Function

9.36E-06-5.48E-02

Organismal Development

4.85E-13-1.01E-03

Organismal Development

9.36E-06-6.03E-02

Gastrointestinal Disease

1.43E-12-8.91E-04

Nervous System Development and Function

1.82E-05-5.83E-02

Infectious Disease

1.63E-12-6.47E-04

Tissue Development

1.82E-05-5.83E-02

Skeletal and Muscular Disorders

3.74E-12-1.13E-03

Organ Morphology

5.23E-05-6.03E-02

Hereditary Disorder

8.81E-12-8.81E-12

Lipid Metabolism

5.97E-05-6.03E-02

Psychological Disorders

8.81E-12-7.60E-11

Small Molecule Biochemistry

5.97E-05-6.03E-02