Fig. 2

Performance evaluation of subsets of the combined database used in COMAN. The combined database was constructed by merging the NCBI bacterial reference genomes non-coding RNAs with eukaryotic ribosomal DNA (both large and small subunits) deposited in the SILVA database. Different subsets of random 10 % and 5 % of the full combined database (indicated by x-axis) were taken and their performance was compared to the BLASTN mapping results from using the full version. For each subset, the “Relative Accuracy” is defined as the number of commonly identified reads between the subset and the full database, divided by the total number of reads identified only by using the subset for mapping. In comparison, the “Relative Sensitivity” is defined as the number of commonly identified reads between the subset and the full database, divided by the total number of reads identified by using the full database