Table 2 Variant distribution per effect and pAAF within each gene group
Variant frequency class | Strong impact | Mild impact | |
|---|---|---|---|
TASR | Very rare (pMAF < 0.01) | 28 (63.6 %) | 51 (29.5 %) |
Rare (pMAF = [0.010–0.019]) | 6 (13.6 %) | 28 (16.2 %) | |
Common (pMAF = [0.020–0.979]) | 10 (22.7 %) | 94 (54.3 %) | |
Total number | 44 | 173 | |
pMAF min-max (average) | 0.0016–0.1910 (0.028) | 0.0016–0.4920 (0.091) | |
AR | Very rare (pMAF < 0.01) | 184 (52.6 %) | 560 (25.5 %) |
Rare (pMAF = [0.010-0.019]) | 41 (11.7 %) | 235 (10.7 %) | |
Common (pMAF = [0.020–0.979]) | 125 (35.7 %) | 1,403 (63.8 %) | |
Total number | 350 | 2,198 | |
pMAF min-max (average) | 0.0017–0.4800 (0.029) | 0.0016–0.4980 (0.0992) |