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Table 2 Top disease and function altered as response to ZEA exposure

From: Microarray based gene expression analysis of Sus Scrofa duodenum exposed to zearalenone: significance to human health

ID

Top diseases and functions

Score

Focus molecules

1

Cell Morphology, Cellular Assembly and Organization, Cellular Function and Maintenance

40

34

2

Metabolic Disease, Neurological Disease, Organismal Injury and Abnormalities

38

33

3

Auditory Disease, Hereditary Disorder, Neurological Disease

38

33

4

Molecular Transport, Hereditary Disorder, Connective Tissue Disorders

35

32

5

Digestive System Development and Function, Endocrine System Development and Function, Organ Morphology

31

30

6

Cellular Movement, Cell-To-Cell Signalling and Interaction, Nervous System Development and Function

31

30

7

Cancer, Cell Death and Survival, Organismal Injury and Abnormalities

31

30

8

Gene Expression, Protein Synthesis, RNA Post-Transcriptional Modification

29

29

9

Cell Death and Survival, Cell Morphology, Infectious Disease

29

29

10

Cardiovascular System Development and Function, Cancer, Cardiovascular Disease

29

29

11

Connective Tissue Disorders, Immunological Disease, Inflammatory Disease

28

28

12

Tissue Development, Post-Translational Modification, Cell Cycle

28

28

13

Cell Cycle, DNA Replication, Recombination, and Repair, Cellular Compromise

26

27

14

Nucleic Acid Metabolism, Small Molecule Biochemistry, Cell Cycle

26

27

15

DNA Replication, Recombination, and Repair, Cell Cycle, Reproductive System Development and Function

26

27

16

Cellular Growth and Proliferation, Embryonic Development, Organ Development

26

27

17

RNA Post-Transcriptional Modification, Developmental Disorder, Hereditary Disorder

26

27

18

Developmental Disorder, Hereditary Disorder, Skeletal and Muscular Disorders

26

27

19

Protein Synthesis, Cancer, Organismal Injury and Abnormalities

26

27

20

Energy Production, Lipid Metabolism, Small Molecule Biochemistry

26

27

21

Cellular Assembly and Organization, Inflammatory Disease, Inflammatory Response

24

26

22

Lipid Metabolism, Molecular Transport, Small Molecule Biochemistry

24

26

23

RNA Post-Transcriptional Modification, Carbohydrate Metabolism, Cellular Compromise

24

26

24

Amino Acid Metabolism, Small Molecule Biochemistry, Cell Signaling

24

26

25

Infectious Disease, Organismal Injury and Abnormalities, Dermatological Diseases and Conditions

24

26