Fig. 2From: The transcriptional and splicing landscape of intestinal organoids undergoing nutrient starvation or endoplasmic reticulum stressInduction of an ER stress transcriptional program in thapsigargin-stimulated enteroids. a Scatterplot of the expression of ER stress response classified genes. Genes above the top red line represent a 2.5-fold increase in expression, while genes below the bottom red line represent genes down-regulated 2.5-fold. b Alternative splicing of transcription factor gene Xbp1 upon thapsigargin treatment, visualized via integrated genome browser (IGV). c Venn diagram analysis of 651 genes upregulated more than 2.5 fold upon 4Â h of thapsigargin treatment, categorized by gene function. d Gene list manually curated based on gene function from the group of 651 upregulated genes. e Venn diagram analysis of 245 genes down-regulated more than 2.5 fold upon 4Â h of thapsigargin treatment, categorized by gene function. f Gene list manually curated based on gene function from the group of 245 downregulated genesBack to article page