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Fig. 3 | BMC Genomics

Fig. 3

From: Transcriptomic analysis reveals sex-specific differences in the expression of Dcl1 and Fis1 genes in the radio-adaptive response of thymocytes to TRP53-mediated apoptosis

Fig. 3

Different protein levels of phosphoserine-18-TRP53, phosphoserine-389-TRP53 and activated-p38MAPK after priming low dose X-ray irradiation in thymocytes of C57BL/6 male and female mice. Left panels, representative Western blots. HIGH indicates exposure to 1.75 Gy of γ-rays. RAR represents radio-adaptive response. LOW denotes exposure to 0.075 Gy of X-rays. Right panels, quantitative data showing normalized relative protein amounts. Each column represents mean of three independent experiments; bars, SD. Open histograms, non-treated thymocytes. Light gray histograms, thymocytes exposed to high dose (1.75 Gy) γ-irradiation. Dark gray histograms, thymocytes exposed to the adaptive regimen of radiation. Black histograms, thymocytes treated with low dose X-irradiation (0.075 Gy). a-b, TRP53. c-d Phosphorylated form of TRP53 at serine 18. e-f Phosphoserine-389-TRP53. g-h Phospho-(Thr180/Tyr182)-p38MAPK

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