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Table 2 Genes involved in apoptosis signaling that show differential transcriptional expression between male and female radioadaptive thymocytes

From: Transcriptomic analysis reveals sex-specific differences in the expression of Dcl1 and Fis1 genes in the radio-adaptive response of thymocytes to TRP53-mediated apoptosis

Probe Name

Gene Symbol

Gene description

log2FC

FDRa

FDRb

GO.Ontology

A_51_P449995

C6

Complement component 6

−1.64

9.89E-03

2.75E-02

GO:0006919

A_51_P458451

Adipoq

Adiponectin

2.36

2.51E-03

3.76E-03

GO:0033034

A_51_P473170

Tnfsf4

Tumor necrosis factor superfamily member 4

2.06

1.67E-04

2.61E-03

GO:0043066

A_52_P304720

Crlf1

Cytokine receptor-like factor 1

−1.97

1.54E-03

4.64E-03

GO:0043524

A_52_P442710

Ndnf

Neuro-derived neurotrophic factor

2.18

2.20E-04

2.06E-03

GO:0043524

A_52_P464831

Dlx1

Distal-less homeobox 1

−2.45

1.50E-04

4.61E-03

GO:0043524

A_55_P1952533

Fis1

Fission 1 (Mitochondrial Outer Membrane) Homolog (S. Cerevisiae)

−2.94

1.06E-04

9.86E-04

GO:0001836

A_55_P1974019

Dapk1

Death associated protein kinase 1

2.18

9.38E-04

7.94E-03

GO:0008624

A_55_P1974845

Pde1a

Phosphodiesterase 1A, Calmodulin-Dependent

−2.24

2.46E-04

3.24E-03

GO:0034391

A_55_P1977431

Cck

Cholecystokinin

1.79

2.67E-04

2.45E-03

GO:0005044

A_55_P1982400

Scara5

Scavenger Receptor Class A, Member 5

−2.91

1.72E-04

3.91E-03

GO:0005044

A_55_P2042101

Prune2

Prune Homolog 2 (Drosophila)

−2.17

2.67E-04

6.68E-03

GO:0006917

A_55_P2044143

Loxl4

Lysyl Oxidase-Like 4

−2.29

4.37E-05

3.99E-04

GO:0005044

A_55_P2089710

Ednrb

Endothelin Receptor Type B

2.57

4.02E-04

1.69E-02

GO:0043066

A_55_P2144686

Dmbt1

Deleted In Malignant Brain Tumors 1

2.78

2.61E-05

2.46E-03

GO:0005044

A_55_P2268221

Arhgap10

Rho GTPase Activating Protein 10

−2.49

2.54E-04

3.04E-03

GO:0043066

A_55_P2280821

Dlc1

Deleted in liver cancer 1

−2.53

2.02E-05

4.49E-04

GO:0006919

  1. log 2 FC log2 Fold Change in gene expression between male and female under RAR treatment; a minus sign denotes down-regulation in radioadapted thymocytes of males as compared with females; FDR a FDR obtained from the moderated t-test for identifying differentially expressed genes between male and female RAR, FDR bFDR obtained from two-way ANOVA for assessing gene expression differences between male and female regarless treatment