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Fig. 3 | BMC Genomics

Fig. 3

From: Copy number variation contributes to cryptic genetic variation in outbreak lineages of Cryptococcus gattii from the North American Pacific Northwest

Fig. 3

Genes overlapping with copy number variants across VGIIa, VGIIb, and VGIIc isolates. Scatter plots represent the number of duplications (X-axis) and deletions (Y-axis) that partially (a) and (b) entirely overlap genes, with marginal density distribution plots for each axis. c–f 95 % confidence intervals and VGIIa, VGIIb, and VGIIc subpopulation means were calculated using 1,000,000 bootstrap replicates. VGIIc has fewer partially duplicated genes than VGIIa (p = 0.034) (c) and more partially deleted genes than VGIIa (p = 0.006) and VGIIb (p = 0.012) (e). VGIIc has fewer whole duplicated genes than VGIIb (p = 0.039) (d), and VGIIa has fewer whole deleted genes than VGIIb (p <6e−5) and VGIIc (p <6e−5) (f). Three individuals from VGIIb with high frequencies of duplication events were removed for scaling in (a) and (b) but were retained for statistical analysis (c–f)

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