Fig. 4From: Copy number variation contributes to cryptic genetic variation in outbreak lineages of Cryptococcus gattii from the North American Pacific NorthwestLoci with distinct subpopulation copy number profiles. a Manhattan plot of VST values (Y-axis) for each 100Â bp bin (X-axis) in the Cryptococcus gattii genome. The horizontal red line represents the upper 99Â % percentile cutoff. Points above this line are considered significantly differentiated CNVs. The five highest VST loci that contain genes are highlighted in yellow (supercontig 11 contains two of the five loci). b Gene copy number estimates for the five highest VST gene-containing loci. The gene ID and VST ID are reported for each locus. Blue, orange, and gray points represent VGIIa, VGIIb, and VGIIc isolates. Functional annotation (PFam domains or gene name) is provided below each plotBack to article page