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Fig. 3 | BMC Genomics

Fig. 3

From: Co-activator candidate interactions for orphan nuclear receptor NR2E1

Fig. 3

Arginines 274 and 276 are highly conserved in NR2E1. UCSC genome browser (https://genome.ucsc.edu/) image depicting NR2E1, and the conservation region of the two most related nuclear receptor binding domains; NR2E3 and NR2F2. A positively charged amino acid is conserved at positions 274 and 276. NR2E1 shows complete identity of arginine 274 and 276 from humans to zebrafish (red rectangles). In NR2E3, 274 is similarly conserved, but 276 becomes lysine in distant species. In NR2F2 a lysine, instead of arginine, is similarly conserved at both positions

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