Table 3 Mean and median distances between PQSs and recombination breakpoints in the P. falciparum 3D7 genome
Breakpoint type | Number | Mean distance from PQS (kb) | Mean distance from PQS in null data (kb) | Median distance from PQS (kb) | Median distance from PQS in null data (kb) | PQS association (median outside C.I.) |
|---|---|---|---|---|---|---|
All | 173 | 132.7 | 301 (Equal) | 16.4 | 180.4 (Equal) | Y |
|  |  | 193.8 (Unequal) | C.I. 11.1–24.3 | 130.5 (Unequal) | Y | |
All translocations | 99 | 163.6 | 300.7 (Equal) | 13.5 | 180.1 (Equal) | Y |
|  |  | 193.4 (Unequal) | C.I. 5.9–53.9 | 130.4 (Unequal) | Y | |
Subtelomeric translocations only | 65 | 109.5 | 300.1 (Equal) | 4.8 | 180.6 (Equal) | Y |
|  |  | 208.8 (Unequal) | C.I. 3.5–8.9 | 129.7 (Unequal) | Y | |
All var coding translocations | 70 | 156.6 | 301.1 (Equal) | 14.7 | 180.6 (Equal) | Y |
|  |  | 181.7 (Unequal) | C.I. 4.1–18.5 | 125.7 (Unequal) | Y | |
Indels | 74 | 91.4 | 300.9 (Equal) | 20 | 179.9 (Equal) | Y |
|  |  | 193.4 (Unequal) | C.I. 11.3–28.4 | 130.3 (Unequal) | Y | |
Var-coding events in progeny of 3D7/HB3 cross | 24 | 56.2 | 300.1 (Equal) | 2.9 | 180.7 (Equal) | Y |
|  |  | 141.1 (Unequal) | C.I. 2.5–11.3 | 98.8 (Unequal) | Y | |
Analysis restricted to subtelomeres | 119 | 91.3 | 133.5 (Equal) | 9.1 | 22.8 (Equal) | Y |
|  |  | 122.1 (Unequal) | C.I. 6.3–15.4 | 18.8 (Unequal) | Y |