Fig. 4
From: Developmental transcriptome of resting cell formation in Mycobacterium smegmatis
Nutrient-starvation induced differentiation in M. smegmatis. Model depicting starvation induced differentiation of log-phase cells into LARCs and SMRCs. Under zero-nutrient starvation (PBS), the development terminates at the septated, multi-nucleoided LARC stage. In the presence of traces of a carbon source (PBS-Tween80), LARCs undergo cell division and separate into SMRCs. Representative genes upregulated early upon starvation are indicated (as shown in Fig. 3). Blue: DNA, red: septa, black: cell envelope. Arrows indicate polar growth of log-phase cells